Human CellExp™ Frizzled-4 / FZD4 Protein, Human recombinant

Catalog number
P1027-10
Name
Human CellExp™ Frizzled-4 / FZD4 Protein, Human recombinant
Size
10 μg
Price
148.00 EUR
Supplier

Details

Target
FZD4
Background
Frizzled-4 (FZD4) is also known as FzE4, CD344, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD4 contains one FZ (frizzled) domain. FZD4 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD4 interacts with MAGI3 and norrin (NDP).
Concentration
N/A
Molecular weight
42.9 kDa
Synonym
FZD4, Frizzled-4, CD344, Fz-4, hFz4, FzE4
Other name
FZD4, Frizzled-4, CD344, Fz-4, hFz4, FzE4
NCBI gene number
8322
NCBI gene
FZD4
Gene source
Human
NCBI number
Q9ULV1
Recombinant
Yes
Source
HEK 293 cells
Purification
> 95%
Tested applications
SDS-PAGE, N/A
Level of endotoxin
N/A
Tested activity
N/A
Biological activity
N/A
Reesults
N/A
Binding ability
N/A
Unit
N/A
Storage condition
-80°C
Shipping under
Gel Pack
Physical appearance
Lyophilized
Physical properties
Lyophilized from 0.22 μm filtered solution in PBS pH 7.5. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
How to reconstitute
Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex.
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants