Human CellExp™ Frizzled-7 / FZD7 Protein, Human recombinant

Catalog number
P1029-10
Name
Human CellExp™ Frizzled-7 / FZD7 Protein, Human recombinant
Size
10 μg
Price
159.00 EUR
Supplier

Details

Target
FZD7
Background
Frizzled-7 (FZD7) is also known as FzE3, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD7 contains one FZ (frizzled) domain. FZD7 is receptor for Wnt proteins. FZD7 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD7 interacts with MAGI3 and DVL1.
Concentration
N/A
Molecular weight
43.3 kDa
Synonym
FZD7, Frizzled-7, FzE3, Fz-7, hFz7
Other name
FZD7, Frizzled-7, FzE3, Fz-7, hFz7
NCBI gene number
8324
NCBI gene
FZD7
Gene source
Human
NCBI number
O75084
Recombinant
Yes
Source
HEK 293 cells
Purification
> 92%
Tested applications
SDS-PAGE, N/A
Level of endotoxin
N/A
Tested activity
N/A
Biological activity
N/A
Reesults
N/A
Binding ability
N/A
Unit
N/A
Storage condition
-80°C
Shipping under
Gel Pack
Physical appearance
Lyophilized
Physical properties
Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH 7.5. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
How to reconstitute
Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex.
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants