Human CellExp™ GITR / TNFRSF18, Rhesus macaque recombinant

Catalog number

P1083-10

Size

10 µg

Price

153.00 EUR

Supplier

Biovision

Order

Details

Target

TNFRSF18

Background

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Concentration

N/A

Molecular weight

41.3 kDa

Synonym

AITR, GITR, TNFRSF18, CD357

Other name

AITR, GITR, TNFRSF18, CD357

NCBI gene number

N/A

NCBI gene

TNFRSF18

Gene source

Rhesus macaque

NCBI number

F7DDV8

Recombinant

Yes

Source

HEK 293 cells

Purification

>95%

Tested applications

SDS-PAGE, N/A

Level of endotoxin

< 1 EU/μg

Tested activity

N/A

Biological activity

N/A

Reesults

N/A

Binding ability

N/A

Unit

N/A

Storage condition

-20°C

Shipping under

Gel pack

Physical appearance

Lyophilized

Physical properties

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally Mannitol or Trehalose is added as a protectant before lyophilization.

How to reconstitute

Reconstitute in sterile deionized water to a concentration of 50 μg/ml.

Aa sequence

N/A

Before use

Centrifuge the vial prior to opening.

Notes

For Research Use Only! Not to be used in humans

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Additional source

Recombinants or rec. proteins

Group

recombinants

About

Monkeys like rhesus's or the rhesus macaque (Macaca mulatta) are the most used apes in laboraty models.