Bromosporine for cell activation
Catalog number
2652-1
Name
Bromosporine for cell activation
Size
1 mg
Price
132.00 EUR
Supplier
Details
Description
Bromosporine is a broad spectrum bromodomain inhibitor (IC₅₀s = 0.41 µM, 0.29 µM, 0.122 µM and 0.017 µM for BRD2, BRD4, BRD9 and CECR2, respectively). At 1 µM, Bromosporine accelerates FRAP recovery of BRD4 and CREBBP, while displaying no activities against TIF1α, BAZ2A, and SMARCA2 even at 10 µM.
Peptide sequence
N/A
CAS number
N/A
Molecular weight
404.44
Category
Biochemicals
Other name
Ethyl (3-methyl-6-(4-methyl-3-(methylsulfonamido)phenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-yl)carbamate
Molecular formula
C₁₇H₂₀N₆O₄S
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~35 mg/ml) or EtOH (~ 10 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
