Caspase-3 inhibitor, Z-DQMD-FMK for cell activation

Catalog number
2782-1
Name
Caspase-3 inhibitor, Z-DQMD-FMK for cell activation
Size
1 mg
Price
142.00 EUR
Supplier

Details

Description
Z-DQMD-FMK is a cell-permeable caspase-3 inhibitor. Inhibits MG-132-induced small cell lung cancer cell death in vitro.
Peptide sequence
Z-Asp(OMe)-Gln-Met-Asp(OMe)-FMK
CAS number
N/A
Molecular weight
685.72
Category
Biochemicals
Other name
Z-DQMD-FMK,Benzyloxycarbonyl-Asp(OMe)-Gln-Met-​Asp(OMe)-fluoromethylketone
Molecular formula
C₂₉H₄₀FN₅O₁₁S
Physical appearance
Lyophilzed solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Y
Purification
≥85% by HPLC
Reconstitute instructions
DMSO (~ 200 mg/ml)
Storage condition
-20°C
Shipping condition
Gel Pack
Maximum time for storage
36 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.