PLX-4720 for cell activation
Catalog number
2813-5
Name
PLX-4720 for cell activation
Size
5 mg
Price
153.00 EUR
Supplier
Details
Description
PLX-4720 is a potent, ATP-competitive B-raf inhibitor (IC₅₀ =160 nM). PLX-4720 preferentially inhibits the active B-Raf(V600E) kinase compared with a broad spectrum of other kinases, and potent cytotoxic effects are also exclusive to cells bearing the V600E allele.
Peptide sequence
N/A
CAS number
918505-84-7
Molecular weight
413.83
Category
Biochemicals
Other name
N-[3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide
Molecular formula
C₁₇H₁₄ClF₂N₃O₃S
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>80 mg/ml)
Storage condition
-20°C
Shipping condition
Gel Pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.
