GW-0742 for cell activation

Catalog number
B1100-5
Name
GW-0742 for cell activation
Size
5 mg
Price
186.00 EUR
Supplier

Details

Description
GW 0742 is a potent and selective PPARδ agonist (EC₅₀ = 1.1 nM) that displays 1,000-fold selectivity over other human PPAR subtypes. Therapeutically has shown to have effect on pulmonary damage, inflammatory and apoptotic parameters in mice. It increases the rate of fatty acid oxidation and provides ischemia /reperfusion injury protection in cardiomyocytes. It has been reported to have neuroprotective properties and enhances interleukin-6 (IL-6), IL-8 expression.
Peptide sequence
N/A
CAS number
317318-84-6
Molecular weight
471.49
Category
Biochemicals
Other name
[4-[[[2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]acetic acid
Molecular formula
C₂₁H₁₇F₄NO₃S₂
Physical appearance
White Solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>40 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.