Lenvatinib for cell activation

Catalog number
B1157-5
Name
Lenvatinib for cell activation
Size
5 mg
Price
142.00 EUR
Supplier

Details

Description
Lenvatinib is a potent inhibitor of multiple receptor tyrosine kinases, with IC₅₀ values of  22 nM, 4 nM, 5.2 nM, 39 nM and 35 nM on VEGFR-1, VEGFR-2, VEGFR-3, PDGFRβ and RET, respectively. It inhibits SCF- and VEGF-induced angiogenesis of human umbilical vein endothelial cells that express the SCF receptor KIT, with IC₅₀ values of 5.2 nM and 5.1 nM, respectively. Lenvatinib inhibits tumor growth in the human small cell lung cancer H146 xenograft model.
Peptide sequence
N/A
CAS number
417716-92-8
Molecular weight
426.85
Category
Biochemicals
Other name
4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide; E7080
Molecular formula
C₂₁H₁₉ClN₄O₄
Physical appearance
Crystalline solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (>35 mg/ml)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.