Kirromycin for cell activation

Catalog number
B1236-5
Name
Kirromycin for cell activation
Size
5 mg
Price
1056.00 EUR
Supplier

Details

Description
Kirromycin belongs to elfermycin group of antibiotics that inhibits as a protein biosynthesis inhibitor. It is shown to interfere with the peptide transfer reaction by acting on elongation factor Tu (EF-tu). This prevents the release of EF-Tu from the bacterial ribosome after GTP hydrolysis, inducing EF-Tu dependent hydrolysis of GTP.
Peptide sequence
N/A
CAS number
50935-71-2
Molecular weight
769.9
Category
Biochemicals
Other name
N-[7-[5-[7-(1,2-dihydro-4-hydroxy-2-oxo-3-pyridinyl)-6-methyl-7-oxo-1,3,5-heptatrienyl]tetrahydro-3,4-dihydroxy-2-furanyl]-6-methoxy-5-methyl-2,4-octadienyl]-alpha-ethyltetrahydro-2,3,4-trihydroxy-5,5-dimethyl-6-(1,3-pentadienyl)-2H-pyran-2-acetamide
Molecular formula
C₄₃H₆₀N₂O₁₂
Physical appearance
Yellow Solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
36 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.