Human CellExp TNF-alpha, Human Recombinant

Catalog number
6482-50
Name
Human CellExp TNF-alpha, Human Recombinant
Size
50 µg
Price
690.00 EUR
Supplier

Details

Synonyms
Human Cellexp Human Recombinant TNF-alpha
Alternates names
TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2.
Taglines
A potent lymphoid factor that exerts cytotoxic effects on a wide range of cells
Biomolecule/Target
NA
NCBI Gene ID #.
7124
NCBI Gene Symbol
TNF
Gene Source
Human
Accession #
P01375
Recombinant
Yes
Source
Human 293 cell expressed
Purity
N/A
Endotoxin Level
< 1.0 EU per 1 μg of protein
Activity (Specifications/test method)
N/A
Biological activity
ED₅₀ is typically < 0.9 ng/mL. The specific activity was determined by the dose-dependent cytotoxity of the TNF alpha sensitive cell line L-929 in the presence of Actinomycin D.
Results
< 0.9 ng/ml
Molecular Weight
17 kDa, non-disulfide bonded homotrimer, glycosylated
Storage Temp.
-20°C
Shipping
gel pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized
Physical form description
Lyophilized in PBS.
Reconstitution Instructions
Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Description
The CellExp TNF-alpha, Recombinant is a α- or alpha protein sometimes glycoprotein present in blood.
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants
Gene
Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.