Anti-Caspase-3 Rabbit Monoclonal Antibody

Catalog number
A1120-50
Name
Anti-Caspase-3 Rabbit Monoclonal Antibody
Size
50 µl
Price
435.00 EUR
Supplier

Details

Antibody Target
Caspase 3
Target Alternative Name
CPP32, CASP3, apopain, procaspase3, CPP32B, SCA-1, CPP-32, Apopain, Yama
Category
NA
Antibody Type
Monoclonal
Species Reactivity
Human
Immunogen Sequence
Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-3 is synthesized as an inactive pro-enzyme (32 kDa) that is processed in cells undergoing apoptosis by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase-3 consists of large (17 kD) and small (12 kD) subunits which associate to form an active enzyme. The active caspase-3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells (e.g., PARP and DFF).
Accession
P42574
Gene ID
836
Appearance
Colorless liquid
Antibody Form
Liquid
Concentration
NA
Formulation
In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Purification
Affinity purified using protein A
Application
IHC, WB
Storage Temp.
-20 °C
Shipping
gel pack
Shelf Life
1 year
Usage
For Research Use Only! Not to be used in humans.
Handling
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.Rabbits are used for polyclonal antibody production by Biovision. Rabbit antibodies are very stable and can be stored for several days at room temperature. Biovision adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Latin name
Oryctolagus cuniculus
French translation
anticorps