Target of this antibody:
Alternative names of antibody target:
Bromodomain-containing protein 8, SMAP, SMAP2, Skeletal muscle abundant protein, Skeletal muscle abundant protein 2, p120, thyroid receptor coactivating protein 120 kDa, TrCP120.
BRD8 interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. BRD8 contains a bromodomain and is thoμght to be a nuclear receptor coactivator. Three alternatively spliced BRD8 transcript variants that encode distinct BRD8 isoforms have been identified.
Clonality of antibody:
This antibody reacts with:
Human, mouse, rat
Synthetic peptide surrounding amino acid 1000 of rat BRD8
Concentration of antibody:
Form of antibody:
Formulation of this antibody:
100 µg (0.5 mg/ml) affinity purified rabbit anti- BRD8 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
This antibody has been succesfully tested for use in following methods:
Western blotting (1-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects BRD8 in Human, mouse and rat samples.
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.