Target of this antibody:
Alternative names of antibody target:
JmjC domain-containing histone demethylation protein 2C, jumonji domain-containing protein 1C, thyroid receptor-interacting protein 8, TRIP-8, TRIP8, JHDM2C, FLJ14374, RP11-10C13.2, DKFZp761F0118, KIAA1380
JMJD1C is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD1C has been identified as a nuclear-receptor coactivator and is a candidate gene for autism.
Clonality of antibody:
This antibody reacts with:
Synthetic peptide surrounding amino acid 1003 of human JMJD1C
Concentration of antibody:
Form of antibody:
Formulation of this antibody:
30 µg (0.5 mg/ml) affinity purified rabbit anti- JMJDC1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
This antibody has been succesfully tested for use in following methods:
Western blotting (1 - 4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects JMJ1DC of human origin. Reactivity to other species has not been tested.
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.