DPP IV Inhibitor, K 579 for cell activation

Catalog number
1963-5
Name
DPP IV Inhibitor, K 579 for cell activation
Size
5 mg
Price
480.00 EUR
Supplier

Details

Description
Cell-permeable. A potent, slow binding dipeptidyl peptidase IV inhibitor with IC₅₀ values of 3, 5, 8, and 8 nM for rat, canine, human and monkey enzymes respectively. Acts as a long-acting hypoglycemic agent.
Peptide sequence
N/A
CAS number
440100-64-1
Molecular weight
328.41
Category
Biochemicals
Other name
(2S)-1-[[[4-Methyl-1-(2-pyrimidinyl)-4-piperidinyl]amino]acetyl]-2-pyrrolidinecarbonitrile
Molecular formula
C₁₇H₂₄N₆O
Physical appearance
Light brown solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~100 mM) or EtOH (~ 20 mM) or 1 eq. HCl (50 mM)
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
48 months
Storage instructions
Protect from light and air
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.