anti-DR5 Antibody

Catalog number
3062-100
Name
anti-DR5 Antibody
Size
DR5 Antibody
Price
316.00 EUR
Supplier

Details

Target of this antibody:
DR5
Alternative names of antibody target:
TNFRSF10B, TRICKB,TRANCE-R, ZTNFR9, CD262, TRICK2A, Apo2, TRAIL-R2, TRICK2, KILLER
Background information:
DR5 is the DD containing receptor for TRAIL, Apo2, TRAIL-R2, TRICK2, or KILLER. DR5 transcript is widely expressed in normal tissues and in many types of tumor cells. Like DR3 and TNFR1, DR5 mediate apoptosis by FADD dependent pathway. Over-expression of DR5 induces apoptosis and activates NFkB.
Antibody host:
Rabbit
Clonality of antibody:
Polyclonal
Isotype:
Rabbit IgG
This antibody reacts with:
Human, mouse
Immunogene sequence:
Synthetic peptide corresponding to residues surrounding amino acid 372 of mouse DR5 precursor
Concentration of antibody:
0.2 mg/ml
Form of antibody:
Liquid
Formulation of this antibody:
100 µg (0.2 mg/ml) immunoaffinity purified rabbit anti-DR5 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification method:
Affinity purified
This antibody has been succesfully tested for use in following methods:
Western blot
Recommended usage:
Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects 60 kDa DR5 in samples of human and mouse origins
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps