anti-HK2 (Hexokinase II) (NT) Antibody

Catalog number
3144-100
Name
anti-HK2 (Hexokinase II) (NT) Antibody
Size
HK2 (Hexokinase II) (NT) Antibody
Price
403.00 EUR
Supplier

Details

Target of this antibody:
HK2 (Hexokinase II)
Alternative names of antibody target:
Hexokinase type II, HK II, Muscle form hexokinase
Background information:
In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase activity is involved in the first step in several metabolic pathways. HK3 is bound to the outer mitochondrial membrane. Its hydrophobic N-terminal sequence may be involved in membrane bindng. It is the predominant hexokinase isozyme expressed in insuline-responsive tissues such as skeletal muscle. The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated wiht the N-terminus. Althoμgh found in NIDDM patients, genetic variations of HK2 do not contribute to the disease.
Antibody host:
Rabbit
Clonality of antibody:
Polyclonal
Isotype:
Rabbit IgG
This antibody reacts with:
Human
Immunogene sequence:
Synthetic peptide selected from the 99 - 158 amino acids of the N-terminal region of human HK2
Concentration of antibody:
0.25 mg/ml
Form of antibody:
Liquid
Formulation of this antibody:
100 µg (0.25 mg/ml) purified rabbit Ig polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification method:
Affinity purified
This antibody has been succesfully tested for use in following methods:
ELISA, Western blot, Immunohistochemistry
Recommended usage:
The antibody can be used for ELISA (0.25 µg/ml), Western blotting (0.5 – 2.5 µg/ml) and Immunohistochemistry (2.5 – 5.0 µg/ml).
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps