Target of this antibody:
Alternative names of antibody target:
TNF-alpha converting enzyme, ADAM17
TACE (TNF-alpha converting enzyme, ADAM17) is a membrane-bound Metalloprotease from the ADAM (a disintegrin and Metalloprotease) family of proteins. It cleaves 26kDa type II membrane-bound precursor of TNF-a into 17 kDa mature form which is secreted. TACE is also known to process other membrane proteins including TNF receptor, TGF-alpha and amyloid protein precursor. Recombinant active untagged TACE amino acid sequence is from Arg 215 to Asn 651
Clonality of antibody:
This antibody reacts with:
Recombinant human protein (BV-L63)
Concentration of antibody:
Form of antibody:
Formulation of this antibody:
100 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2
This antibody has been succesfully tested for use in following methods:
Western blot: 1:200
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.