anti-TLR8 (TAntibody (Clone 44B05)

Catalog number
anti-TLR8 (TAntibody (Clone 44B05)
TLR8 (TAntibody (Clone 44B05)
425.00 EUR


Target of this antibody:
Alternative names of antibody target:
LR8 , Anti-TLR8 , CD288 , CD 288 , MGC119599 , # MGC119600
Background information:
The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1 contains an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFkB and sμggests that these receptors are involved in mediating inflammatory responses. TLR6 is highly homologous to TLR1, and like other members of TLR family, it induces NFkB signaling upon activation. TLR8 gene contains three exons, two of which have coding function. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes.
Antibody host:
Clonality of antibody:
Mouse IgG1
This antibody reacts with:
Immunogene sequence:
Recombinant human TLR8
Concentration of antibody:
1.0 mg/ml
Form of antibody:
Formulation of this antibody:
100 µl (1 mg/ml) Protein G purified mouse anti-TLR8 monoclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Purification method:
Affinity purified
This antibody has been succesfully tested for use in following methods:
Western blot, Flow cytometry
Recommended usage:
Western blotting (1:200-1000 dilutions) and FACS analysis. Ramos cell lysate can be used as a positive control and a 120 kDa band is detected in Western blotting. For FACS analysis, we recommend 1-4 ml per million cells. However, the optimal conditions should be determined individually.
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.