anti-Phospho-BRCA1 Antibody

Catalog number
3674-100
Name
anti-Phospho-BRCA1 Antibody
Size
Phospho-BRCA1 Antibody
Price
403.00 EUR
Supplier

Details

Target of this antibody:
Phospho-BRCA1
Alternative names of antibody target:
BRCA1, BRCA pSer 1280, Breast Cancer Gene 1, Breast Cancer 1, Early Onset; Breast-Ovarian Cancer Susceptibility
Background information:
BRCA1 is a breast cancer susceptibility gene that was localized to chromosome 17q. Mutations within this gene are believed to account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer. The BRCA1 gene is expressed in numerous tissues, including breast and ovary, and encodes a predicted protein of 1863 amino acids. Like many other genes involved in familial cancer, BRCA1 appears to encode a tumor suppressor, a protein that acts as a negative regulator of tumor growth.
Antibody host:
Rabbit
Clonality of antibody:
Polyclonal
Isotype:
Rabbit IgG
This antibody reacts with:
Human
Immunogene sequence:
Phosphorylated synthetic peptide surrounding Serine 1189 of human BRCA1
Concentration of antibody:
0.5 mg/ml
Form of antibody:
Liquid
Formulation of this antibody:
100 µg (0.5 mg/ml) peptide affinity purified rabbit anti-phosphorylated BRCA1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Purification method:
Affinity purified
This antibody has been succesfully tested for use in following methods:
Western blot
Recommended usage:
Western blotting (1-2 µg/ml). However, the optimal conditions should be determined individually. Other applications have not been tested yet. Detect human BRCA1 when phosphorylated at Ser1189.
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps