Target of this antibody:
Alternative names of antibody target:
IL-17, IL17, IL 17, Interluekin-17, Interluekin 17, interluekin
IL-17 was identified from a CD4+ T cells DNA library. IL-17 can be induced from primary peripheral blood CD4+ T cells upon stimulation. The cytokine exhibits a high degree of amino acid identity with HVS13, an open reading frame from a T lymphotropic Herpesvirus saimiri and with murine CTLA8. Supernatant from cells transfected with IL-17 induced IL-16 and IL-18 production and enhanced the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts. IL-17 is a disulfide-linked homodimer of two 31.0 kDa subunits, each containing 136 amino acid residues.
Clonality of antibody:
This antibody reacts with:
E. coli expressed human IL-17
Concentration of antibody:
Form of antibody:
Formulation of this antibody:
100 µg (0.5 mg/ml) affinity purified rabbit anti-human IL-17 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 10 mM EDTA, and 0.02% thymersal.
This antibody has been succesfully tested for use in following methods:
Western blot, ELISA
Western blot analysis (0.5-1 µg/ml) and ELISA (2-4 µg/ml). However, the optimal conditions should be determined individually.
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.