anti-CITED2 Antibody (NT)

Catalog number
5286-100
Name
anti-CITED2 Antibody (NT)
Size
CITED2 Antibody (NT)
Price
403.00 EUR
Supplier

Details

Target of this antibody:
CITED2
Alternative names of antibody target:
Cbp/p300-interacting transactivator 2, melanocyte-specific gene 1-related gene 1, MSG-related protein 1, MRG1, melanocyte specific gene 2, MSG2, ER154-like, ASD8, VSD2
Background information:
CITED2 was initially identified as a potential transcriptional activator with significant homology to MSG1, a melanocyte-specific nuclear protein. CITED2 interacts with the histone acetyltransferase p300/CBP and acts as a coactivator to several DNA-binding transcription factors such as HIF-1 and AP-2. CITED2 also controls proliferation of mouse embryonic fibroblasts via the polycomb group genes Bmi-1 and Mel18 and the tumor suppressor Ink4a/Arf. CITED2 has also been found to be an essential regulator of adult hematopoietic stem cells (HSCs), with conditional deletion of CITED2 in the adult mouse resulting in the loss of HSCs, multilineage bone marrow failure and increased lethality.
Antibody host:
Rabbit
Clonality of antibody:
Polyclonal
Isotype:
Rabbit IgG1
This antibody reacts with:
Human, mouse, rat
Immunogene sequence:
CITED2 antibody was raised against an 18 amino acid peptide near the amino terminus of human CITED2.
Concentration of antibody:
1 mg/ml
Form of antibody:
Liquid
Formulation of this antibody:
100 µg (1 mg/ml) in 1X PBS containing 0.02 % sodium azide.
Purification method:
Affinity chromatography purified via peptide column
This antibody has been succesfully tested for use in following methods:
Western blot, ELISA
Recommended usage:
Western Blot: 1 - 2 μg/ml, ELISA. However, the optimal conditions should be determined individually.
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps