anti-UHRF1 Antibody

Catalog number
6144-100
Name
anti-UHRF1 Antibody
Size
UHRF1 Antibody
Price
414.00 EUR
Supplier

Details

Target of this antibody:
UHRF1
Alternative names of antibody target:
FLJ21925, ICBP90, MGC138707, Np95, RNF106, hNP95
Background information:
UHRF1, also named as ICBP90, NP95 and RNF106, is a putative E3 ubiquitin protein ligase. It may participate in methylation dependent transcriptional regulation. UHRF1 binds to inverted 5'­CCAAT­3' box 2 in the TOP2A promoter, and activates TOP2A expression. It is important for G1/S transition and may be involved in DNA repair and chromosomal stability. UHRF1's ability to repress its direct target gene expression is dependent on PHD (UHRF1) binding to unmodified H3R2.
Antibody host:
Rabbit
Clonality of antibody:
Polyclonal
Isotype:
Rabbit IgG
This antibody reacts with:
Human
Immunogene sequence:
Recombinant protein of human UHRF1
Concentration of antibody:
1 mg/ml
Form of antibody:
Liquid
Formulation of this antibody:
100 µg of antibody in 100 µl PBS containing 0.02% sodium azide, 50% glycerol, pH 7.3
Purification method:
Affinity purified
This antibody has been succesfully tested for use in following methods:
Western blot, Immunohistochemistry, Immunoprecipitation, Immunofluorescene, CHIP
Recommended usage:
Western blot: 1:500 – 1:2000, IHC: 1:50 – 1:200, IF: 1:20 – 1:50, IP: 1:20 – 1:50, CHIP: 1:20 – 1:50. However, the optimal conditions should be determined individually.
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps