flt3-Ligand, human recombinant

Catalog number
4085-50
Name
flt3-Ligand, human recombinant
Size
50 μg
Price
645.00 EUR
Supplier

Details

Synonyms
Fms-related tyrosine kinase 3 ligand
Alternates names
Fms-related tyrosine kinase 3 ligand, Short name=Flt3 ligand, Short name=Flt3L, SL cytokine
Taglines
A member of a small family of growth factors that stimulate the proliferation of hematopoietic cells
Biomolecule/Target
Flt-3 Ligand
NCBI Gene ID #.
2323
NCBI Gene Symbol
Flt3-L
Gene Source
Human
Accession #
P49771
Recombinant
Yes
Source
E. coli
Purity
≥98%
Activity (Specifications/test method)
N/A
Biological activity
The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of human AML5 cells is 1 x 10⁶ units/mg.
Molecular Weight
17.6 kDa
Storage Temp.
-20°C
Shipping
Gel pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized protein
Physical form description
Sterile filtered and lyophilized with no additives. The protein may appear as a haze of film, which is difficult to see at the bottom of the vial.
Reconstitution Instructions
Reconstitute in H₂O to a concentration of 0.1 – 1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Description
FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
Additional source
Recombinants or rec. proteins
Group
recombinants