GM-CSF, human recombinant

Catalog number
4100-100
Name
GM-CSF, human recombinant
Size
100 μg
Price
775.00 EUR
Supplier

Details

Synonyms
Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-α
Alternates names
Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-α, Colony-stimulating factor, Molgramostin, Sargramostim
Taglines
A cytokine that stimulates the bone marrow to produce granulocytes and stem cells
Biomolecule/Target
GM-CSF
NCBI Gene ID #.
1437
NCBI Gene Symbol
CSF2
Gene Source
Human
Accession #
P04141
Recombinant
Yes
Source
E. coli
Purity
≥98%
Activity (Specifications/test method)
N/A
Biological activity
The ED₅₀ determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is 1 x 10⁷ units/mg.
Molecular Weight
14.6 kDa
Storage Temp.
-20°C
Shipping
Gel pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized protein
Physical form description
Lyophilized from 10 mM Sodium Citrate, pH 3.5
Reconstitution Instructions
Reconstitute in H₂O to a concentration of 0.1-1.0 µg/µl. This solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or –20°C for future use.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Gene
Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts that functions as a cytokine. The pharmaceutical analogs of naturally occurring GM-CSF are called sargramostim and molgramostim. Reconstitution It is recommended that sterile ddH2O containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of not less than 1 mg/mL of the cytokine.
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants