IGF-I, human recombinant

Catalog number
4119-5000
Name
IGF-I, human recombinant
Size
5 mg
Price
945.00 EUR
Supplier

Details

Synonyms
insln-Like Growth Factor 1, Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF
Alternates names
insln-Like Growth Factor 1, Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF
Taglines
Human IGF-1 from E.Coli, AOF, ≥98% pure, biologically active, cell culture tested
Biomolecule/Target
IGF-I
NCBI Gene ID #.
3479
NCBI Gene Symbol
IGF1A
Gene Source
Human
Accession #
P01343
Recombinant
Yes
Source
E. coli
Purity
≥98%
Activity (Specifications/test method)
N/A
Biological activity
EC50 is typically 21.6-54.7 ng/ml. The activity was determined using dose dependent stimulation of Balbc 3T3 cell line.
Results
21.6-54.7 ng/ml
Molecular Weight
7.6 kDa
Storage Temp.
-20°C
Shipping
Gel pack
Shelf Life
1 year
Concentration
N/A
Appearance
Recombinant IGF-1 is available as a lyophilized powder
Physical form description
IGF-1 protein is lyophilized with no additives
Reconstitution Instructions
Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can be diluted into other buffered solutions or stored at 4°C for 1 week or –20°C for future use.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Description
IGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades.
Additional source
Recombinants or rec. proteins
Group
recombinants