anti-CD105/Endoglin Antibody (Center E395)

Catalog number
6800-100
Name
anti-CD105/Endoglin Antibody (Center E395)
Size
CD105/Endoglin Antibody (Center E395)
Price
316.00 EUR
Supplier

Details

Target of this antibody:
CD105
Alternative names of antibody target:
ENG; END; Endoglin
Background information:
Endoglin (ENG, CD105) is an auxiliary receptor for the TGF-β receptor complex, functioning in related signaling pathways. Endoglin is a transmembrane protein that exists as a disulfide-linked homodimer. It is mainly expressed in vascular and connective tissues and in endothelial and stromal cells. Upregulated endoglin expression has been reported during wound healing and tumor vascularization, and in inflammatory tissues and developing embryos. Mutations in endoglin have been found to be a causal factor of hereditary hemorrhagic telangiectasia (HHT), a disease characterized by malformation of vascular structure. The importance of this protein for normal and tumor vascular function makes it a good marker for endothelial cell proliferation as well as a potential therapeutic target in cancer.
Antibody host:
Rabbit
Clonality of antibody:
Polyclonal
Isotype:
Rabbit IgG
Clone:
N/A
This antibody reacts with:
Human, Mouse.
Immunogene sequence:
This CD105 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-409 amino acids from the Central region of human CD105.
Concentration of antibody:
N/A
Form of antibody:
Liquid
Formulation of this antibody:
In PBS with 0.09% (W/V) sodium azide.
Purification method:
Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
This antibody has been succesfully tested for use in following methods:
Western blot, IHC, FACS.
Recommended usage:
WB: 1:1000, IHC: 1:10 – 1:50, FC: 1:10 – 1:50.
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps