anti-Setd1b polyclonal antibody

Catalog number
6843-50
Name
anti-Setd1b polyclonal antibody
Size
Setd1b polyclonal antibody
Price
251.00 EUR
Supplier

Details

Target of this antibody:
Setd1b
Alternative names of antibody target:
SET1B, KMT2G
Background information:
SETD1B (UniProt/Swiss-Prot entry Q9UPS6) is a component of the SET1 histone methyltransferase (HMT) complex. This complex specifically methylates lysine 4 of histone H3, but only if the neighboring lysine 9 residue is not yet methylated. Methylation of H3K4 represents a specific tag for epigenetic transcriptional activation. SETD1B shows a non-overlapping localization with SETD1A, suggesting that both proteins play a specific role in the epigenetic control of chromatin structure and gene expression.
Antibody host:
Rabbit
Clonality of antibody:
Polyclonal
Isotype:
Rabbit IgG
Clone:
N/A
This antibody reacts with:
Mouse.
Immunogene sequence:
Polyclonal antibody raised in rabbit against mouse Setd1b (Set domain containing 1B), using a 3 KLH-conjugated synthetic peptides containing sequences from the central part of the protein
Concentration of antibody:
N/A
Form of antibody:
Liquid
Formulation of this antibody:
In PBS with 0.05% (W/V) sodium azide.
Purification method:
Whole Anti-Sera
This antibody has been succesfully tested for use in following methods:
Western blot, ELISA.
Recommended usage:
ELISA: 1:100 – 1:500, Western Blot: 1:500.
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Group
Polyclonals and antibodies
About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
French translation
anticorps