anti-DNMT3A polyclonal antibody

Catalog number
6849-25
Name
anti-DNMT3A polyclonal antibody
Size
DNMT3A polyclonal antibody
Price
371.00 EUR
Supplier
Biovision
Order

Details

Target of this antibody:
DNMT3A
Alternative names of antibody target:
DNA Methyltransferase 3a
Background information:
DNMT3A catalyzes the genome wide de novo methylation of CpG residues. DNA methylation on CpG residues by DNMT3A regulates gene expression and is essential for development. DNMT3A is strongly expressed in embryonic stem cells, but low in adult somatic cells. DNA methylation is coordinated with methylation of histones. DNMT3A binds to SETDB1 and HDAC1, and is involved in the repression of transcription from promoters containing an E2F binding site.
Antibody host:
Rabbit
Clonality of antibody:
Polyclonal
Isotype:
Rabbit IgG
Clone:
N/A
This antibody reacts with:
Human.
Immunogene sequence:
Polyclonal antibody raised in rabbit against human DNMT3A, (DNA methyltransferase 3A), using a KLH-conjugated synthetic peptide corresponding to amino acids 92-106.
Concentration of antibody:
N/A
Form of antibody:
Liquid
Formulation of this antibody:
In PBS with 0.05% sodium azide and 0.05% ProClin 300.
Purification method:
Affinity Purified
This antibody has been succesfully tested for use in following methods:
Western blot, ELISA, IP.
Recommended usage:
Western Blot: 1:2,500, ELISA: 1:100, IP: 2 µg/IP.
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Group
Polyclonals and antibodies
About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
French translation
anticorps