Target of this antibody:
Alternative names of antibody target:
T-cell surface glycoprotein CD1e membrane-associated; hCD1e; R2G1; CD1e
CD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members.
Clonality of antibody:
This antibody reacts with:
Human, Mouse, Rat
This CD1e antibody is generated from KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD1e. The exact sequence is proprietary.
Concentration of antibody:
Form of antibody:
Formulation of this antibody:
1 mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen Affinity chromatography
This antibody has been succesfully tested for use in following methods:
WB: 1:500 - 1:1000, IF/IC: 1:100 – 1:500
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.