anti-BCRP (ABCG2) Antibody

Catalog number
anti-BCRP (ABCG2) Antibody
BCRP (ABCG2) Antibody
403.00 EUR


Target of this antibody:
Alternative names of antibody target:
Breast Cancer Resistance Protein, BCRP1, ATP-binding cassette sub-family G member 2, ATP binding cassette sub family G (WHITE) member 2, ABCG2, Mitoxantrone resistance associated protein, MXR, MXR1
Background information:
BCRP, also called ABCG2, is encoded by the ABCG2 gene. BCRP is a well-characterized ABC-transporter (which limits uptake or mediates efflux of a wide variety of drugs, carcinogens, dietary toxins across cellular membranes). It is an ATP-dependent pump with broad substrate specificity. Significant expression has been observed in the placenta and it has been shown to have a role in protecting the fetus from xenobiotics in the maternal circulation. It plays protective roles in blocking absorption at the apical membrane of the intestine, and at the blood-testis barrier, the blood–brain barrier and the membranes of hematopoietic progenitor and other stem cells. At the apical membranes of the liver and kidney, it enhances excretion of xenobiotics. In the lactating mammary gland, it has a role on excreting vitamins such as riboflavin and biotin into milk.
Antibody host:
Clonality of antibody:
Rabbit Ig
This antibody reacts with:
Immunogene sequence:
Synthetic peptide corresponding to amino acids around position 160 of human ABCG2
Concentration of antibody:
Form of antibody:
Formulation of this antibody:
Each vial contains 5mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3, 0.05 mg Thimerosal
Purification method:
Immunogen affinity purified antibody
This antibody has been succesfully tested for use in following methods:
Western Blot
Recommended usage:
WB: 1:1000-1:5000 of 0.5 mg/ml stock
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The vial should be centrifuged to collect the lyophilized solid before reconstituting
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation