Target of this antibody:
Alternative names of antibody target:
TGM2, Protein-glutamine gamma-glutamyltransferase 2, Tissue transglutaminase, TG, TGC, TGase C, Transglutaminase H, TGase H, TGase-2
Tissue transglutaminase, a 78-kDa calcium dependent enzyme (EC 184.108.40.206), is found both in the intracellular and the extracellular spaces of various types of tissues. TG2 crosslinks proteins between the ε-amino group of a lysine residue and the γ-carboxamide group of glutamine residue, creating an inter- or intramolecular bond that is highly resistant to proteolysis (protein degradation). TG2 also possesses deamidation, GTP-binding/hydrolyzing, and isopeptidase activities. Intracellular TG2 is thought to play an important role in apoptosis, while extracellular TG2 has been linked to cell adhesion, ECM stabilization, wound healing, receptor signaling, cellular proliferation, and cellular motility.
Clonality of antibody:
This antibody reacts with:
Human, Mouse, Rat
human Transglutaminase-2 recombinant protein (Cat. No. 7700)
Concentration of antibody:
Form of antibody:
Formulation of this antibody:
100 µg (0.5 mg/ml) of antibody in PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin®, and 50 % glycerol.
Affinity purified rabbit IgG
This antibody has been succesfully tested for use in following methods:
Western blot: 1-4 µg/ml
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.