anti-Phospho-PDGFR beta (Tyr716) polyconal Antibody

Catalog number
anti-Phospho-PDGFR beta (Tyr716) polyconal Antibody
Phospho-PDGFR beta (Tyr716) polyconal Antibody
371.00 EUR


Target of this antibody:
Alternative names of antibody target:
PDGFRB; PDGFR; PDGFR1; Platelet-derived growth factor receptor beta; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-derived growth factor receptor 1
Background information:
Platelet-derived growth factor (PDGF) refers to a family of disulphide-bonded dimeric isoforms that are important for growth and survival, and which function in several types of connective tissue cell. There are four members of the platelet-derived growth factor (PDGF) family: PDGF-A, PDGF-B, PDGF-C and PDGF-D (spinal cord-derived growth factor-B or iris-expressed growth factor). Their biological effects are mediated via two tyrosine kinase receptors, PDGFR-α and PDGFR-β. PDGF-mediated signaling is critical for development of many organ systems. PDGF-D has a two-domain structure similar to PDGF-C and is secreted as a disulphide-linked homodimer, PDGF-DD. Upon limited proteolysis, PDGF-DD is activated and becomes a specific agonistic ligand for PDGFR-β. PDGF-D is expressed in fibroblastic adventitial cells, cultured endothelial cells and in a variety of tumor cell lines.
Antibody host:
Clonality of antibody:
Rabbit IgG
This antibody reacts with:
Immunogene sequence:
Synthetic peptide
Concentration of antibody:
1 mg/ml
Form of antibody:
Formulation of this antibody:
100 ug (1mg/ml) of antibody in 0.01M Tris-HCl, pH 8.0, 0.15M NaCl, and 0.02% sodium azide.
Purification method:
Affinity purified rabbit IgG using protein G
This antibody has been succesfully tested for use in following methods:
WB, Immunoblot, ELISA
Recommended usage:
Western blot, Immunoblot: 0.5-2 μg/ml, ELISA
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation