anti-Anti-HER2 (Trastuzumab), humanized Antibody
Catalog number
A1046-100
Name
anti-Anti-HER2 (Trastuzumab), humanized Antibody
Size
Anti-HER2 (Trastuzumab), humanized Antibody
Price
371.00 EUR
Supplier
Details
Target of this antibody:
HER2
Alternative names of antibody target:
Herceptin
Background information:
Trastuzumab is a recombinant humanized monoclonal immunoglobulin G1 kappa antibody that binds with high affinity and specificity to the extracellular domain of the HER2 receptor. A growth factor receptor gene, human epidermal growth factor receptor (HER2), is amplified in 25 to 30 % of breast cancers and in these cases the encoded protein is present in abnormally high levels in the malignant cells. Trastuzumab is used to treat adjuvant and metastatic breast cancer as well as metastatic gastric cancer.
Antibody host:
Human
Clonality of antibody:
Monoclonal
Isotype:
Human IgG1
This antibody reacts with:
Human
Immunogene sequence:
Recombinant human epidermal growth factor receptor 2 (HER2)
Concentration of antibody:
2 mg/ml
Form of antibody:
Liquid
Formulation of this antibody:
100 ug (2mg/ml) of antibody in Phosphate buffered saline, pH 7.4.
Purification method:
human IgG1 was expressed in a human cell line. IgG was purified from CHO cell culture supernatant by protein A chromatography.
This antibody has been succesfully tested for use in following methods:
Neutralization, ELISA
Recommended usage:
Neutralization : 1-20 μg/ml; ELISA: 2μg/ml
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps
