anti-Anti-EGFR (Cetuximab), Chimeric Antibody
Catalog number
A1047-100
Name
anti-Anti-EGFR (Cetuximab), Chimeric Antibody
Size
Anti-EGFR (Cetuximab), Chimeric Antibody
Price
371.00 EUR
Supplier
Details
Target of this antibody:
EGFR
Alternative names of antibody target:
Erbitux
Background information:
Cetuximab is a recombinant human/mouse chimeric epidermal growth factor receptor (EGFR) monoclonal antibody. Epidermal growth factor receptor (EGFR) is a receptor found on both normal and tumor cells that is important for cell growth. Cetuximab is an EGFR inhibitor, used to treat cancer by blocking the activity of EGFR and keep cancer from growing. Cetuximab can form a bridge that trigger an immune response by binding to the EGFR on the tumor cells. It is used for the treatment of EGFR-expressing, metastatic colorectal cancer.
Antibody host:
Human/Mouse chimeric
Clonality of antibody:
Monoclonal
Isotype:
Human IgG1
This antibody reacts with:
Human
Immunogene sequence:
Human A431 cells
Concentration of antibody:
2 mg/ml
Form of antibody:
Liquid
Formulation of this antibody:
100 ug (2mg/ml) of antibody in Phosphate buffered saline, pH 7.4.
Purification method:
human IgG1 was expressed in a mouse cell line. IgG was purified from mouse cell culture supernatant by protein A chromatography.
This antibody has been succesfully tested for use in following methods:
Neutralization, ELISA
Recommended usage:
Neutralization : 1-20 μg/ml; ELISA: 2μg/ml
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps
