TNF-beta, human recombinant

Catalog number
4345-1000
Name
TNF-beta, human recombinant
Size
1 mg
Price
3500.00 EUR
Supplier

Details

Synonyms
Tumor Necrosis Factor-β, TNFSF1, Lymphotoxin-α (LT-α)
Alternates names
Tumor Necrosis Factor-β, TNFSF1, Lymphotoxin-α (LT-α)
Taglines
A protein that controls proliferation, cellular differentiation, & other functions in most cells
Biomolecule/Target
TGF-beta
NCBI Gene ID #.
4049
NCBI Gene Symbol
TNFB
Gene Source
Human
Accession #
P01374
Recombinant
Yes
Source
E. coli
Purity
≥98%
Activity (Specifications/test method)
N/A
Biological activity
The ED₅₀ as determined by the cytolysis of murine L929 cells in the presence of actinomycin D is <0.05 ng/ml, corresponding to a specific activity of>2 x 10⁷ units/mg.
Molecular Weight
18.6 kDa
Storage Temp.
-20°C
Shipping
Gel pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized protein
Physical form description
Sterile filtered and lyophilized with no additives
Reconstitution Instructions
Reconstitute in PBS to a concentration of 1 mg/ml. This solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use. For long term storage, it is recommended to add a carrier protein (0.1% HAS or BSA).
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants
Gene
Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.