Leptin, murine recombinant

Catalog number
4367-02
Name
Leptin, murine recombinant
Size
200 μg
Price
235.00 EUR
Supplier

Details

Synonyms
OB Protein, Obesity Protein, OBS, Obesity factor.
Alternates names
OB Protein, Obesity Protein, OBS, Obesity factor.
Taglines
Adipose-derived hormone which regulates energy intake & energy expenditure
Biomolecule/Target
Leptin
NCBI Gene ID #.
16846
NCBI Gene Symbol
LEP
Gene Source
Mouse
Accession #
P41160
Recombinant
Yes
Source
E. coli
Purity
N/A
Activity (Specifications/test method)
N/A
Biological activity
Determined in an in vivo assay using the ob/ob mouse obesity model and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 µg leptin/gm of body weight for 7 days. Significant effects on body weight, food consumption, and plasma glucose levels were observed to saline-treated controls.
Results
N/A
Molecular Weight
16.2 kDa
Storage Temp.
-20°C
Shipping
Gel pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized protein
Physical form description
Lyophilized with no additives
Reconstitution Instructions
Reconstitute in 10 mM HCl to a concentration of 1 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Gene
Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
Additional source
Recombinants or rec. proteins
Group
recombinants