anti-Anti-Human Ephrin Type A receptor 2 (1C1), Human IgG1 Antibody

Catalog number
A1095-200
Name
anti-Anti-Human Ephrin Type A receptor 2 (1C1), Human IgG1 Antibody
Size
Anti-Human Ephrin Type A receptor 2 (1C1), Human IgG1 Antibody
Price
697.00 EUR
Supplier

Details

Target of this antibody:
EPHA2
Alternative names of antibody target:
EphA2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK
Background information:
This antibody binds to human Ephrin type-A receptor 2, a receptor tyrosine kinase that binds to membrane-bound ephrin-A ligands residing on adjacent cells, triggering contact-dependent signaling into neighboring cells. Involved in pattern formation during development, angiogenesis and osteoblastogenesis. Eph2A has also been found to be expressed in a variety of cancers. This antibody acts as an agonist of Eph2A signaling.
Antibody host:
Recombinant
Clonality of antibody:
Monoclonal
Isotype:
Human IgG1, kappa
Clone:
1C1
This antibody reacts with:
Human
Immunogene sequence:
Soluble human sEphA2, residues 183-510
Form of antibody:
Liquid
Formulation of this antibody:
200 µg affinity purified human antibody in phosphate-buffered saline (PBS) containing 0.02% Proclin 300
Purification method:
Affinity purified using protein A
This antibody has been succesfully tested for use in following methods:
ELISA; FC; WB
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Test
Biovision supplies antibodies that are for research of human proteins.
French translation
anticorps