anti-Alpha 2 HS Glycoprotein Antibody

Catalog number
A1111-100
Name
anti-Alpha 2 HS Glycoprotein Antibody
Size
Alpha 2 HS Glycoprotein Antibody
Price
338.00 EUR
Supplier

Details

Target of this antibody:
AHSG
Alternative names of antibody target:
Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein, Fetuin-A
Background information:
Alpha 2 macroglobulin (A2M) is a major serum protein found at concentrations of 240 mg per 100 ml in men and 290 mg per 100 ml in women. It functions as a broad-spectrum protease-binding protein. It is produced by the liver, and is a major component of the alpha-2 band in protein electrophoresis. It is a large plasma glycoprotein that has long been known as an irreversible inhibitor of a variety of proteinases. More recently, it has been reported that numerous growth factors, cytokines and hormones bind to alpha 2M through diverse mechanisms. A2M is also produced in the brain where it binds multiple extracellular ligands and is internalized by neurons and astrocytes. In the brain of Alzheimer's disease (AD) patients, A2M has been localized to diffuse amyloid plaques. A2M also binds soluble beta-amyloid, of which it mediates degradation. Protease-conjugated alpha2-macroglobulin is selectively bound by cells contacting the body fluids and alpha2-macroglobulin and its protease cargo are then internalized and degraded in secondary lysosomes of those cells.
Antibody host:
Rabbit
Clonality of antibody:
Polyclonal
Isotype:
Rabbit IgG
Clone:
N/A
This antibody reacts with:
Human
Immunogene sequence:
Human alpha 2 SH Glycoprotein (Cat. No. 7548)
Concentration of antibody:
0.5 mg/ml
Form of antibody:
Liquid
Formulation of this antibody:
In PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin® and 50 % glycerol
Purification method:
Affinity purified rabbit IgG
This antibody has been succesfully tested for use in following methods:
WB
Recommended usage:
WB: 1-4 µg
Storage information:
Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions:
gel pack
How to handle this antibody:
The antibody solution should be gently mixed before use.
Description
The anti-Alpha 2 HS Glycoprotein Antibody is a α- or alpha protein sometimes glycoprotein present in blood.This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps