Target of this antibody:
Alternative names of antibody target:
Alpha-1 type I collagen, Collagen alpha-1(I) chain
Collagen, a major component of the extracellular matrix, is a fibrous protein that provides tensile strength to tissues giving them structural integrity. Collagen and its derivative, gelatin, have been widely used in medical, pharmaceutical and consumer products for more than 100 years. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function. The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms.
Clonality of antibody:
This antibody reacts with:
Recombinant human collagen-I
Concentration of antibody:
Form of antibody:
Formulation of this antibody:
In PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin® and 50 % glycerol
Affinity purified rabbit IgG
This antibody has been succesfully tested for use in following methods:
WB, Dot blot
WB: 1-4 µg, Dot blot: 1-4 µg
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Collagen Types in bones and muscles can be hydrolyzed and used in human grafts. ( Type II )