Noggin, human recombinant

Catalog number
4675-20
Name
Noggin, human recombinant
Size
20 μg
Price
355.00 EUR
Supplier

Details

Synonyms
none
Alternates names
NOG
Taglines
An inhibitor of TGF-β signal transduction
Biomolecule/Target
NA
NCBI Gene ID #.
9241
NCBI Gene Symbol
NOG
Gene Source
Human
Accession #
Q13253
Recombinant
Yes
Source
E. coli
Purity
≥95%
Activity (Specifications/test method)
N/A
Biological activity
Determined by its ability to inhibit 5 ng/ml of BMP-4-induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED₅₀ for the effect is 0.05-0.08 µg/ml of Noggin
Results
0.05-0.08 µg/ml
Molecular Weight
23.1 kDa
Storage Temp.
-20°C
Shipping
Blue ice
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized protein
Physical form description
Sterile filtered and lyophilized with no additives
Reconstitution Instructions
Reconstitute in H₂O to a concentration of 0.1 to 1.0 mg/ml. Note: Due to solubility reasons the protein should be kept at low pH. This solution can then be diluted into other aqueous buffers
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants