Actinomycin D (10 mM) for cell activation

Catalog number
1036-50
Name
Actinomycin D (10 mM) for cell activation
Size
50 µl
Price
126.00 EUR
Supplier

Details

Description
An antineoplastic antibiotic. Inhibits DNA-primed RNA polymerase by complexing with DNA via deoxyguanosine residues. A DNA-intercalator with growth inhibitory activity against certain leukemias and sarcomas. At higher concentrations, DNA polymerase is inhibited. Inhibits cell growth and colony formation in synchronized HeLa cells. A potent inducer of apoptosis in many cell lines (1).
Peptide sequence
N/A
CAS number
50-76-0
Molecular weight
1255.5
Category
Apoptosis Inducer
Other name
Actinomycin C1, Actinomycin IV, Dactinomycin
Molecular formula
C₆₂H₈₆N₁₂O₁₆
Physical appearance
Liquid
Supplied with
In DMSO (10 mM)
Is this a salt?
No
Is it cell-permeable?
No
Purification
>98% by TLC
Reconstitute instructions
N/A
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
6 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.