Caspase-2 Substrate VDVAD-pNA for cell activation

Ready-to-use colorimetric substrate for caspase-2/Ich-1 and related caspases that recognize the amino acid sequence VDVAD. Caspase-2 and related caspase activity can be quantified by detection of free pNA after cleavage from the peptide substrate VDVAD-pNA at OD405 nm using a spectrophotometer or plate reader. The ready-to-use caspase substrate provides an economic alternative for researchers who perform large amount of caspase assays.

Ac-Val-Asp-Val-Ala-Asp-pNA

N/A

679.7

Caspase Substrate

Ac-VDVAD-pNA, Caspase-2 Substrate, Colorimetric, VDVAD-pNA

C₂₉H₄₁N₇O₁₂

Liquid

DMSO (4 mM)

No

No

>98% by HPLC

N/A

-20°C

gel pack

12 months

Protect from light and moisture

cell

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.For cells, cell lines and tissues in culture till half confluency.