Calpain Inhibitor Z-LLY-FMK for cell activation

Catalog number
1125-20C
Name
Calpain Inhibitor Z-LLY-FMK for cell activation
Size
20 µl (10 mM)
Price
186.00 EUR
Supplier

Details

Description
A potent, cell-permeable, and irreversible inhibitor of calpain II (k₂ = 28,900 M⁻¹s⁻¹). Also acts as an inhibitor of cathepsin L (k₂= 680,000 M⁻¹s⁻¹).
Peptide sequence
Z-Leu-Leu-Tyr-FMK
CAS number
N/A
Molecular weight
557.7
Category
Calpain
Other name
Z-LLY-FMK, Calpain Inhibitor(fluoromethylketone)
Molecular formula
C₃₀H₄₀FN₃O₆
Physical appearance
Liquid
Supplied with
DMSO (10 mM)
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
>95% by HPLC
Reconstitute instructions
N/A
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
12 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.