Granzyme B Inhibitor Z-AAD-CH2Cl for cell activation

Catalog number
1128-20C
Name
Granzyme B Inhibitor Z-AAD-CH2Cl for cell activation
Size
20 µl (10 mM)
Price
208.00 EUR
Supplier

Details

Description
A synthetic peptide that irreversibly inhibits granzyme B activity. The inhibitor is designed as a methyl ester to facilitate cell permeability.
Peptide sequence
Z-Ala-Ala-Asp(OMe)-CMK
CAS number
N/A
Molecular weight
455.89
Category
Granzyme B
Other name
Z-AAD-CMK, Granzyme B Inhibitor(chloromethylketone)
Molecular formula
C₂₀H₂₆ClN₃O₇
Physical appearance
Liquid
Supplied with
DMSO (10 mM)
Is this a salt?
No
Is it cell-permeable?
No
Purification
Single spot by TLC
Reconstitute instructions
N/A
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
12 months
Storage instructions
Protect from light and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.