Caspase-8 Inhibitor, Q-IETD-OPh for cell activation

Catalog number
1176-1
Name
Caspase-8 Inhibitor, Q-IETD-OPh for cell activation
Size
1 mg
Price
295.00 EUR
Supplier

Details

Description
A second-generation capase-8 inhibitor that is potent, cell permeable, irreversible and nontoxic.
Peptide sequence
N/A
CAS number
N/A
Molecular weight
785.78
Category
Caspase Inhibitor
Other name
Q-IE(OMe)-TD(OMe)-OPh; Quinolyl-Ile-Glu(OMe)-Thr-Asp(OMe)-OPh
Molecular formula
C₃₈H₄₅F₂N₅O₁₁
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
N/A
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.