Human Recombinant PAI-1

Catalog number
6377-100
Name
Human Recombinant PAI-1
Size
100 μg
Price
445.00 EUR
Supplier

Details

Synonyms
Human Recombinant PAI-1
Alternates names
Plasminogen activator inhibitor-1, SERPINE1, PAI, PAI1, PLANH1.
Taglines
Activator of plasminogen and fibrinolysis
Biomolecule/Target
NA
NCBI Gene ID #.
5054
NCBI Gene Symbol
SERPINE1
Gene Source
Human
Accession #
P05121
Recombinant
Yes
Source
E. Coli
Purity
N/A
Endotoxin Level
N/A
Activity (Specifications/test method)
N/A
Biological activity
Specific activity, the IC50 value is <56 nM. Measured by its ability to inhibit uPA cleavage of the substrate Z-GGR-AMC.
Molecular Weight
45 kDa (400 aa, 24-402 aa + NT His-Tag)
Storage Temp.
-20°C
Shipping
gel pack
Shelf Life
1 year
Concentration
1 mg/ml
Appearance
Liquid
Physical form description
1 mg/ml solution in 150 mM Na2HPO4 (pH 6.6) containing 0.5 mM NaCl, 2 mM Glutathione and 0.01% Tween-80.
Reconstitution Instructions
N/A
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Gene
Plasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitor or serpin E1 is a protein that in humans is encoded by the SERPINE1 gene. Elevated PAI-1 is a risk factor for thrombosis and atherosclerosis
Additional source
Recombinants or rec. proteins
Group
recombinants