VX-702 for cell activation

Catalog number
1598-1
Name
VX-702 for cell activation
Size
1 mg
Price
387.00 EUR
Supplier

Details

Description
A p38 MAP kinase inhibitor. VX-702 dose-dependently inhibited the production of IL-6, IL-1β and TNFα (IC₅₀ = 59, 122 and 99 ng/ml, respectively). Pre-incubation of platelets with VX-702 (1 µM) completely or partially inhibited platelet agonist induced p38 activation (IC₅₀= 4 to 20 nM).
Peptide sequence
N/A
CAS number
745833-23-2
Molecular weight
404.32
Category
Biochemicals
Other name
2-(2,4-Difluorophenyl)-6-(1-(2,6-difluorophenyl)ureido)nicotinamide
Molecular formula
C₁₉H₁₂F₄N₄O₂
Physical appearance
White soild
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥99% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
RT
Maximum time for storage
24months
Storage instructions
Protect from air and moisture
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.