Human CellExp™ BMP-7, Human Recombinant

Catalog number
6446-10
Name
Human CellExp™ BMP-7, Human Recombinant
Size
10 μg
Price
382.00 EUR
Supplier

Details

Background
BMP7 belongs to the transforming growth factor-beta (TGFβ) superfamily. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Based on its expression early in embryogenesis, BMP-7 has a proposed role in early development. In addition, the fact that BMP-7 is closely related to BMP5 has led to speculation of possible bone inductive activity.
Concentration
N/A
Molecular weight
30 to 38 kDa, homodimer, glycosylated.
Synonym
Human Cellexp Human Recombinant BMP-7
Other name
Osteogenic Protein 1, BMP-7
NCBI gene number
655
NCBI gene
BMP7
Gene source
Human
NCBI number
P18075
Recombinant
Yes
Source
Human 293 cell expressed
Purification
≥95%
Tested applications
SDS-PAGE, N/A
Level of endotoxin
<1.0 EU per 1 μg of protein
Tested activity
N/A
Biological activity
ED₅₀ is typically 50 to 250 ng/mL. The specific activity was determined by the dose dependent induction of alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line).
Reesults
50 to 250 ng/ml
Binding ability
N/A
Unit
N/A
Storage condition
-80°C
Shipping under
gel pack
Physical appearance
Lyophilized
Physical properties
Lyophilized from a solution of 50 mM sodium acetate, pH 4.5, with 50 mM NaCl.
How to reconstitute
Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants