Human CellExp™ FGF-4, Human Recombinant

Catalog number
6449-50
Name
Human CellExp™ FGF-4, Human Recombinant
Size
50 μg
Price
904.00 EUR
Supplier

Details

Background
FGF4 is involved in mitogenic and cell survival activities and takes part in a range of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF4 possess oncogenic transforming activity. FGF4 and FGF3, oncogenic growth factors are localized on chromosome 11. Co-amplification of both factors was found in several kinds of human tumors. FGF4 functions in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Human FGF-4 shares high homology and cross-reactivity with the mouse protein.
Concentration
N/A
Molecular weight
17 and 27 kDa, monomer, glycosylated
Synonym
Human Cellexp Human Recombinant FGF-4
Other name
HBGF4, FGF-4, FGF4, KFGF, HSTF1
NCBI gene number
2249
NCBI gene
FGF4
Gene source
Human
NCBI number
P08620
Recombinant
Yes
Source
Human cell expressed
Purification
≥95%
Tested applications
SDS-PAGE, N/A
Level of endotoxin
<1.0 EU per 1 μg of protein
Tested activity
N/A
Biological activity
ED₅₀ is typically 0.25 to 1.25 ng/mL. The specific activity was determined by the dose- dependent stimulation of the proliferation of the Balb/3T3 cell line.
Reesults
0.25 to 1.25 ng/ml
Binding ability
N/A
Unit
N/A
Storage condition
-80°C
Shipping under
gel pack
Physical appearance
Lyophilized
Physical properties
Lyophilized from a PBS solution.
How to reconstitute
Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants