Human CellExp™ FGF-7 (KGF), Human Recombinant

Catalog number
6450-10
Name
Human CellExp™ FGF-7 (KGF), Human Recombinant
Size
10 μg
Price
371.00 EUR
Supplier

Details

Background
FGF-7 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.
Concentration
N/A
Molecular weight
17 and 30 kDa, monomer, glycosylated
Synonym
Human Cellexp Human Recombinant FGF-7 (KGF)
Other name
HBGF-7, FGF7, FGF-7, KGF
NCBI gene number
2252
NCBI gene
FGF7
Gene source
Human
NCBI number
P21781
Recombinant
Yes
Source
Human cell expressed
Purification
≥95%
Tested applications
SDS-PAGE, N/A
Level of endotoxin
<1.0 EU per 1 μg of protein
Tested activity
N/A
Biological activity
ED₅₀ is typically 1.5 to 7.5 ng/mL. The specific activity was determined by the Dose-dependent stimulation of the proliferation of 4MBr-5 cells (monkey epithelial cell line).
Reesults
1.5 to 7.5 ng/ml
Binding ability
N/A
Unit
N/A
Storage condition
-80°C
Shipping under
gel pack
Physical appearance
Lyophilized
Physical properties
Lyophilized from a PBS solution.
How to reconstitute
Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
Aa sequence
N/A
Before use
Centrifuge the vial prior to opening.
Notes
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants